Plots

PVR

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PA_sys

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mPAP

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Info

β-adrenoceptor antagonists reported as potential future PH treatment targets - Neurohormonal regulation
Sommer, Natascha, et al. "Current and future treatments of pulmonary arterial hypertension." British journal of pharmacology 178.1 (2021): 6-30.

NCBI Gene Summary for ADM2 Gene

  • This gene encodes a member of the calcitonin gene-related peptide (CGRP)/calcitonin family of hormones that play a role in the regulation of cardiovascular homeostasis, prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. [provided by RefSeq, Jul 2015]

GeneCards Summary for ADM2 Gene

ADM2 (Adrenomedullin 2) is a Protein Coding gene. Diseases associated with ADM2 include Immunodeficiency 53 and Coronary Stenosis. Among its related pathways are GPCR downstream signalling and Presynaptic function of Kainate receptors. Gene Ontology (GO) annotations related to this gene include protein-containing complex binding and hormone activity. An important paralog of this gene is ADM.