• This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  

FBLN2 (Fibulin 2) is a Protein Coding gene. Diseases associated with FBLN2 include Cutis Laxa and Brachyolmia Type 4 With Mild Epiphyseal And Metaphyseal Changes. Among its related pathways are Elastic fibre formation and Extracellular matrix organization. Gene Ontology (GO) annotations related to this gene include calcium ion binding and extracellular matrix binding. An important paralog of this gene is FBLN1.