• Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. [provided by RefSeq, Jul 2008]
  

GNB4 (G Protein Subunit Beta 4) is a Protein Coding gene. Diseases associated with GNB4 include Charcot-Marie-Tooth Disease, Dominant Intermediate F and Riboflavin Transporter Deficiency. Among its related pathways are ADORA2B mediated anti-inflammatory cytokines production and Thromboxane signalling through TP receptor. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and protein-containing complex binding. An important paralog of this gene is GNB2.