• The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
  

NFIC (Nuclear Factor I C) is a Protein Coding gene. Diseases associated with NFIC include Mechanical Ectropion and Marshall-Smith Syndrome. Among its related pathways are RNA Polymerase III Transcription Initiation and Gene expression (Transcription). Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and DNA-binding transcription activator activity, RNA polymerase II-specific. An important paralog of this gene is NFIA.